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Redemption, Period [Domain] Debt Instrument, Redemption, Period [Domain] Insider Trading Arrangements [Line Items] AOCI Attributable to Parent, Net of Tax [Roll Forward] AOCI Attributable to Parent, Net of Tax [Roll Forward] Share price (in dollars per share) Share Price Note purchase agreement, percent of aggregate outstanding principal amount, cash balance required Note Purchase Agreement, Percent of Aggregate Outstanding Principal Amount, Cash Balance Required Note Purchase Agreement, Percent of Aggregate Outstanding Principal Amount, Cash Balance Required Aggregate intrinsic value of options Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value Debt Instrument, Redemption, Period One Debt Instrument, Redemption, Period One [Member] Period after first commercial sale Collaborative Arrangement, Rights and Obligations, Period After First Commercial Sale Collaborative Arrangement, Rights and Obligations, Period After First Commercial Sale Entity Registrant Name Entity Registrant Name Material Terms of Trading Arrangement Material Terms of Trading Arrangement [Text Block] Award Timing Method Award Timing Method [Text Block] Maximum aggregate commercial milestone payments Collaborative Arrangement, Rights and Obligations, Maximum Aggregate Commercial Milestone Payments Collaborative Arrangement, Rights and Obligations, Maximum Aggregate Commercial Milestone Payments Adjustment to Compensation, Amount Adjustment to Compensation Amount Document Period End Date Document Period End Date Compensation Actually Paid vs. Net Income Compensation Actually Paid vs. Net Income [Text Block] Note purchase agreement, amount available for funding at the option of the company and counterparty Note Purchase Agreement, Amount Available For Funding At The Option Of The Company And The Counterparty Note Purchase Agreement, Amount Available For Funding At The Option Of The Company And The Counterparty Adoption Date Trading Arrangement Adoption Date Peer Group Issuers, Footnote Peer Group Issuers, Footnote [Text Block] Less: Accumulated depreciation Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment Schedule of Fair Value, Financial Assets and Liabilities Measured on Recurring Basis Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block] Exercisable at end of period (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price Entity Central Index Key Entity Central Index Key Liabilities Liabilities, Fair Value Disclosure [Abstract] Compensation expense recognized Share-Based Payment Arrangement, Expense Non-Rule 10b5-1 Arrangement Terminated Non-Rule 10b5-1 Arrangement Terminated [Flag] Income tax expense Income Tax Expense (Benefit) Personnel related expenses Employee-related Liabilities, Current Fair Value Measurement Fair Value Disclosures [Text Block] Name Trading Arrangement, Individual Name Other comprehensive income Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent Thereafter Lessee, Operating Lease, Liability, to be Paid, after Year Four Lessee, Operating Lease, Liability, to be Paid, after Year Four Issuance of ordinary shares under ATM program, net of issuance costs Stock Issued During Period, Value, New Issues Debt Securities, Available-for-Sale [Line Items] Debt Securities, Available-for-Sale [Line Items] Weighted-average remaining lease term Operating Lease, Weighted Average Remaining Lease Term Compensation Actually Paid vs. Company Selected Measure Compensation Actually Paid vs. Company Selected Measure [Text Block] Amendment Flag Amendment Flag Note purchase agreement, value Note Purchase Agreement, Value Note Purchase Agreement, Value 2026 Lessor, Operating Lease, Payment to be Received, Year Two Money Market fund Money Market Funds [Member] Milestone payment, period Milestone Payment, Period Milestone Payment, Period Cash and Cash Equivalents [Axis] Cash and Cash Equivalents [Axis] Cash and cash equivalents Money Market fund, included in Cash and cash equivalents, amortized cost Cash and Cash Equivalents, at Carrying Value Shares withheld to pay employee withholding tax on share-based compensation (in shares) Share-Based Payment Arrangement, Shares Withheld for Tax Withholding Obligation Other comprehensive (loss) income: Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent, Alternative [Abstract] Weighted-average discount rate Operating Lease, Weighted Average Discount Rate, Percent Interest paid Interest Paid, Excluding Capitalized Interest, Operating Activities Share-based payment awards issued in period (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Shares Issued in Period Heptares Heptares Therapeutics Limited [Member] Heptares Therapeutics Limited Assets Assets, Fair Value Disclosure [Abstract] Debt instrument, basis spread on variable rate Debt Instrument, Basis Spread on Variable Rate Compensation Actually Paid vs. Other Measure Compensation Actually Paid vs. Other Measure [Text Block] Long term debt Long-Term Debt, Excluding Current Maturities Weighted average ordinary shares outstanding - diluted (in shares) Weighted Average Number of Shares Outstanding, Diluted At-the-market At-the-market [Member] At-the-market Schedule of Balance Sheet Information Related to Leases Assets And Liabilities, Lessee [Table Text Block] Assets And Liabilities, Lessee [Table Text Block] Grantee Status [Domain] Grantee Status [Domain] Forgone Recovery, Explanation of Impracticability Forgone Recovery, Explanation of Impracticability [Text Block] Period after contractual agreement ends Collaborative Arrangement, Rights and Obligations, Period After Contractual Agreement Ends Collaborative Arrangement, Rights and Obligations, Period After Contractual Agreement Ends Interest income Interest Income (Expense), Nonoperating, Net Operating expenses: Operating Expenses [Abstract] Purchases of property and equipment Payments to Acquire Property, Plant, and Equipment Company Selected Measure Amount Company Selected Measure Amount Additional paid-in capital Additional Paid-in Capital [Member] Balance Sheet Location [Axis] Balance Sheet Location [Axis] Total assets Assets Name Awards Close in Time to MNPI Disclosures, Individual Name Maximum aggregate development milestone payments Collaborative Arrangement, Rights and Obligations, Maximum Aggregate Development Milestone Payments Collaborative Arrangement, Rights and Obligations, Maximum Aggregate Development Milestone Payments Cover [Abstract] Subsequent Event Subsequent Events [Text Block] Share-based compensation expense APIC, Share-Based Payment Arrangement, Increase for Cost Recognition Fair Value, Recurring Fair Value, Recurring [Member] Other liabilities Other Liabilities, Noncurrent Non-NEOs Non-NEOs [Member] Total Lessee, Operating Lease, Liability, to be Paid Short-term investments Short-Term Investments Weighted average interest rate Long-Term Debt, Weighted Average Interest Rate, over Time Subsidiary, Sale of Stock [Line Items] Subsidiary, Sale of Stock [Line Items] Net decrease in cash and cash equivalents Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect Cash flows from financing activities: Net Cash Provided by (Used in) Financing Activities [Abstract] Non-PEO NEO Non-PEO NEO [Member] Lease, renewal term Lessee, Operating Lease, Renewal Term Equity Component [Domain] Equity Component [Domain] Adjustment to Compensation: Adjustment to Compensation [Axis] Non-GAAP Measure Description Non-GAAP Measure Description [Text Block] Debt Instrument [Line Items] Debt Instrument [Line Items] Weighted average ordinary shares outstanding - basic (in shares) Weighted Average Number of Shares Outstanding, Basic Entity Current Reporting Status Entity Current Reporting Status Loss from operations Operating Income (Loss) Sufficient funding term (at least) Cash And Cash Equivalents, At Carrying Value, Sufficient Funding Term Cash And Cash Equivalents, At Carrying Value, Sufficient Funding Term Cumulative payments under note purchase agreement, including interest Cumulative Payments Under Note Purchase Agreement, Including Interest Cumulative Payments Under Note Purchase Agreement, Including Interest Reclassifications Reclassification, Comparability Adjustment [Policy Text Block] Debt Instrument, Redemption, Period Two Debt Instrument, Redemption, Period Two [Member] Other Property, Plant and Equipment, Other Types [Member] Consolidated Entities [Domain] Consolidated Entities [Domain] Debt instrument, redemption price, percentage of principal amount redeemed Debt Instrument, Redemption Price, Percentage of Principal Amount Redeemed Pay vs Performance Disclosure Pay vs Performance Disclosure [Table] Statement [Line Items] Statement [Line Items] Property and Equipment, net and Capitalized Software under Cloud Computing Arrangements Property, Plant and Equipment, Policy [Policy Text Block] Vested and expected to vest at end of period (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number Note Purchase Agreement Note Purchase Agreement Note Purchase Agreement [Member] Note Purchase Agreement Weighted-Average Remaining Contractual Term Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Additional Disclosures [Abstract] Forgone Recovery due to Disqualification of Tax Benefits, Amount Forgone Recovery due to Disqualification of Tax Benefits, Amount Schedule of Debt Schedule of Debt [Table Text Block] Awards Close in Time to MNPI Disclosures Awards Close in Time to MNPI Disclosures [Table] Schedule of Debt Securities, Fair Value of U.S. Treasury Securities and Money Market Fund Debt Securities, Available-for-Sale [Table Text Block]